Laboratory mouse - Wikipedia
WEBThe albino laboratory mouse is an iconic model organism for scientific research in a variety of fields. An SCID. Intermediate coat colour. Kept as a pet. The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory mice are usually of the species ...
Albino Mouse - an overview | ScienceDirect Topics
WEBBALB/c Mouse. H. Nakamura, in Brenner's Encyclopedia of Genetics (Second Edition), 2013. Synopsis. BALB/c mice are albino and have pink eyes with white skin hair. Coat color genotypes are A/A, b/b, and c/c. BALB/c mice are inbred strain and now over 230 generations from their origin in New York in 1920.
000058 - Strain Details - The Jackson Laboratory
WEBThis unique characteristic makes these mice ideal for creation of novel strains with targeted mutations (gene knockouts). B6 albino mice are used to generate blastocysts that can be used for microinjection of genetically modified C57BL/6J embryonic stem cells.
BALB/c - Wikipedia
WEBBALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation. [1]
MGI - Biology of the Laboratory Mouse - The Jackson Laboratory
WEBThe widely distributed Swiss albino mice, largely noninbred, are mainly derived from two males and seven females which Clara J. Lynch of the Rockefeller Institute obtained from A. de Coulon of Lausanne in 1926 (Lynch, 1961, personal communication). The original stock probably came from Paris.
Biology and Diseases of Mice - PMC - National Center for …
WEBSep 2, 2007 · The first autosomal genes, albino and pink-eyed dilution, were linked in 1915 (Haldane et al., 1915). Extensive linkage maps and an impressive array of inbred strains are now available to expedite sophisticated genetic research. Mice have 40 chromosomes that are differentiated by the size and patterns of transverse bands.
Light and the laboratory mouse - ScienceDirect
WEBApr 15, 2018 · Mice are the organism of choice in biomedical research due to their small size, rapid reproductive cycles, coupled with the availability of extensive genomic information and well-established transgenic resources.
Albino Mouse - an overview | ScienceDirect Topics
WEBAlbinism is characterized by reduced melanin in the skin, hair and eyes. Hair follicles of albino mice contain melanocytes, but do not produce melanin. Like melanism, albinism has evolved repeatedly in widely divergent taxa, often through mutations in the same set of genes (Table 1).
Retinal and cortical visual acuity in a common inbred albino mouse …
WEBMay 28, 2021 · We compared the spatial resolution (acuity) of albino mice (BALB/c) with that of pigmented mice (C57BL/6J). We used a high-throughput pattern electroretinogram (PERG) and pattern visual evoked potential (PVEP) method for objective assessment of retinal and cortical acuity, as well as optomotor head-tracking response/ reflex (OMR).
The Tyr (albino) locus of the laboratory mouse | Mammalian …
WEBTyrosinase is encoded at the albino (Tyr) locus of the mouse on Chromosome 7 (Kwon et al. 1989b), where multiple natural mutations and manmade mutations (Fig. 1) have helped to define the functions and interactions of this enzyme with other proteins that together effect normal pigmentation.