Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

The Texans lost to the Seattle Seahawks 27-19 on Monday night even though Anderson scored the first touchdown of his NFL career. Anderson had a strip-sack of quarterback Sam Darnold and recovered the fumble in the end zone.

Mac Jones triggered a $400,000 bonus with a win for the 49ers. Discover the details of his contract bonus incentive.

Robert Saleh, Klay Kubiak, Mac Jones, and George Kittle speak with reporters following practice on Thursday at the SAP Performance Facility in Santa Clara.Robert Saleh, George Kittle, Klay Kubiak, Mac

His contract includes a clause that pays Jones $400,000 if San Francisco wins four games in which he plays at least 25 percent of the 49ers’ offensive snaps. Jones has taken every offensive snap in his five games.

Mac Jones continues under center for the 49ers (5-2) when they travel to Houston for a Sunday afternoon tilt against the Texans (2-4). Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the Rams.

Who is 'Matt Jones'? 49ers' QB depth chart has NFL fans confused originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. Some words sound very similar. Or in this case, names, like Matt and Mac.

Here are the anytime touchdown picks worth backing when San Francisco plays Houston in Week 8 of the 2025 NFL season