As a response to her comment, on South Park's most recent episode, Noem is shown as someone who cares a lot about how she looks. She has got a full glam squad doing her hair and makeup. The show also makes fun of how her makeup slowly melts off, which makes her call in a makeup team to fix her look.

Kristi Noem, the United States Secretary of Homeland Security, appeared on Glenn Beck’s radio show and slammed “South Park” as “so lazy” and “petty” after she became the Comedy Central series’ latest target (via The Daily Beast).