The increase in pancreatic cancer cases is closely tied to high insulin levels. Now, a new study reveals a direct link between high insulin levels, common among patients with obesity and Type 2 ...

Pancreatic cancer often lurks as a silent disease. With no known symptoms, it can progress undetected and spread to other organs. According to the National Cancer Institute, more than 60,000 Americans ...

The pancreas, located behind the stomach, manages the energy supply in our body. It does so by secreting proteins (enzymes) responsible for glucose – the body's main fuel – reaching other organs when ...

(A) Representative H&E staining image of a mouse pancreas. The black arrow denotes the acinar cells and the white arrow denotes the islet. (B) Representative image of electron microscopy analysis of ...

ITGB6 as an inhibitor of T-cell killing via modulation of paracrine TGFβ signaling in pancreatic ductal adenocarcinoma. Phase I study of ProAgio, an αvβ3 integrin cytotoxin, in patients with ...

Dr. Otis Brawley answers the question: 'Atypical Small Acinar Proliferation?' March 16, 2009 -- Question: What does atypical small acinar proliferation (ASAP) mean? Answer: Atypical small acinar ...

Hans Clevers, PhD, has been working on organoids from the beginning. He was group leader for twenty years at the Hubrecht Institute and has been head of pharma research and early development (pRED) of ...

The pathogenesis of chronic pancreatitis (CP) is complex and involves interactions among different cell types, including pancreatic acinar, ductal and stellate cells (PSC). Researchers from ...

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may ...