IN 1945, Gubner and Szucs 1 compared the efficacy of several drugs in the treatment of acute rheumatic fever. They reported that a group of patients treated with ascorbic acid and a succinate compound ...

A collaborative network led by Cincinnati Children's Hospital Medical Center has received an $8 million grant from the Leducq Foundation to fund a project that will look to identify and validate ...

The clinical diagnosis of acute rheumatic fever (ARF) may be challenging; however, a constellation of signs including new valvular insufficiency, cardiomegaly, and heart failure should readily prompt ...

In a prospective study, patients with acute rheumatic fever (ARF) and active rheumatic heart disease (ARHD) showed a significant increase in CD4⁺ T cells, CD22⁺ B cells, and CD4:CD8 cell ratio but a ...

Research led by the University of Otago in New Zealand has uncovered the strongest evidence yet that household overcrowding is a major risk factor for acute rheumatic fever and streptococcal ...

The incidence of acute rheumatic fever (ARF) has shown a steady decline in the United States. Attack rates in most recent studies have averaged 0.5 per 100,000 population leading to the concept that ...

*Rates are crude, average annual rates per 100,000 population. † Rate ratios calculated in relation to reference value. ARF indicates acute rheumatic fever; CI, confidence interval; NZDep, New Zealand ...

ELECTRON microscope investigations of ‘fibrinoid’ in Aschoff nodules from biopsy specimens of the left atrial appendage in mitral stenosis have shown that collagen fibrils are intimately related to ...

A streptococcal infection may lead to other diseases, such as acute rheumatic fever, pediatric autoimmune neuropsychiatric disorders, and post-streptococcal glomerulonephritis. Group A beta-hemolytic ...

This ecologic study found a positive association between household crowding and ARF incidence and that this effect persisted after controlling for age, ethnicity, household income, and the density of ...