While scientists have known for years that African trypanosomes cause sleeping sickness, they've been left scratching their heads as to how these tiny single-celled organisms communicate. A University ...

Aurélien Vigneron, Michelle B. O’Neill, Brian L. Weiss, Amy F. Savage, Olivia C. Campbell, Shaden Kamhawi, Jesus G. Valenzuela, Serap Aksoy Proceedings of the National Academy of Sciences of the ...

Researchers have deciphered a crucial signaling mechanism that enables trypanosomes to reach the salivary glands of the flies. LMU researchers have deciphered a crucial signaling mechanism that ...

Belgian scientists say that small antibodies taken from the dromedary may prove useful in treating tropical parasites such as the African trypanosome, which causes sleeping sickness. Penetrating the ...

Parasites that cause the deadly illness known as sleeping sickness can spread beyond their native Africa as a result of mutations to key genes, a study shows. The findings reveal that climate change ...

Trypanosoma brucei, the causative agent of African sleeping sickness, represents a paradigm of parasite evolution and immune evasion. Its ability to periodically change its variant surface ...

Researchers from Sebastian Zoll’s group at IOCB Prague determined the first cryo-EM structures of a surface receptor of the human-infective parasite Trypanosoma brucei gambiense in complex with human ...

Cyanotriazole compounds are fast-acting topoisomerase II poisons that can selectively and rapidly kill trypanosome parasites that cause Chagas disease and African sleeping sickness, according to a new ...

L uísa Figueiredo, a parasitologist at the University of Lisbon, has a long-standing relationship with parasites. It all began during her time as an exchange student at Imperial College London when ...

LMU researchers have deciphered a crucial signaling mechanism that enables trypanosomes to reach the salivary glands of the flies. Tsetse flies are common across much of Africa. They feed on the blood ...