Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity. Hydrogen sulfide (H2S) treatment restored chromatin interactions and ...

Using a variety of laboratory and animal models, the team found that cysteine fuels the production of the antioxidant ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

Checkpoint inhibitors have transformed cancer treatment over the past decade, helping hundreds of thousands of patients by ...

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the ...

Meet the Jekyll and Hyde of the immune system: activated CD8⁺ T cells. On June 24 in Nature Immunology, researchers led by Dorian McGavern at the National Institutes of Health introduce a granzyme ...

More than 35,000 men in the United States die from prostate cancer each year. Now, a new study reveals the immune cell ...

Published on March 23, 2026, in Volume 2, article number 18 of the journal Immunity & Inflammation , the review begins by systematically outlining ...