The Louisville Cardinals are hosting the Clemson Tigers in a Week 12 college football game. Follow live updates.

Nov 8, 2025; Louisville, Kentucky, USA; Louisville Cardinals wide receiver Caullin Lacy (5) returns a kickoff against the California Golden Bears during the second half at L&N Federal Credit Union Stadium. California defeated Louisville 29-26. Mandatory Credit: Jamie Rhodes-Imagn Images / Jamie Rhodes-Imagn Images

The 2026 matchup marks the first time Notre Dame has played at the home of the New England Patriots. Meanwhile, Navy played in Foxborough back in 2023 when Gillette Stadium hosted the Army-Navy Game for the first time.

A wave of quarterback movement, coaching changes, and blue-chip frustration is about to reshape college football

There will be a chance for rain, with the best chance of rain for the day happening after the Pitt game. Rain totals should be less than a tenth of an inch. Wind speeds don't look to pick up until behind the front, with Sunday morning being windy.

John Beam, a legendary college football coach and athletic director who gained national fame through Netflix’s hit series "Last Chance U," has died after being shot on campus.Beam was rushed to the hospital in critical condition after the incident at Laney College in Oakland,

The 15-day Disney-YouTube TV blackout has become Disney's longest ever, with more marquee college football games and the Dallas Cowboys approaching.

Clemson vs. Louisville Vegas odds. Louisville is favored by three points against Clemson, per the VegasInsider.com consensus betting line. The point spread opened at Louisville -2