Life begins with a quiet but precise choreography inside the nucleus. For decades, scientists believed that a newly ...
For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...
A new study from the Italian Institute of Technology (IIT), in collaboration with Uppsala University (Sweden) and AstraZeneca, shows how computational chemistry and supercomputers can help scientists ...
Even after decades of peering into cells, biologists are still finding surprises. In a twist, researchers at the University of Virginia and the National Institutes of Health uncovered a new organelle, ...
RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...
Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...
Some of the signs of aging in human cells originate in the cell nucleus, because the packaged form of DNA changes with age.
They did this by culturing human embryonic stem cells in a series of steps with just two chemical signals over 48 hours, after which the cells organised themselves into the inner and outer layers of ...