Identifying conditions that maximize the structural stability of a biologic’s native state is essential for developing therapeutics, formulations, and process development conditions. In this GEN ...

PTIR calculates the rates at which originally monomeric proteins are transformed into aggregates at various temperatures under initial-rate settings. Utilizing SMSLS for identical conditions generates ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are ...

Researchers have developed a 'self-driving' microscope that can predict the onset of misfolded protein aggregation - a hallmark of neurodegenerative disease - as well as analyze the biomechanical ...

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

Patients with Huntington's disease have a genetic mutation that triggers proteins to misfold and clump together in the brain. These clumps interfere with cell function and eventually lead to cell ...

Purdue University researchers have taken the first steps to treat Alzheimer’s disease, Parkinson’s disease and Type 2 diabetes by creating multiple patent-pending compounds shown to inhibit protein ...

Biotherapeutic pipelines don’t just juggle monoclonal antibodies anymore, they need to be ready for protein conjugates like ADCs and for teeny tiny peptides. Even beyond new modalities, automation is ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington’s, Alzheimer’s and Parkinson’s. But to the human eye, proteins that are ...