We report on a family with recessive resistance to the action of thyrotropin-releasing hormone (TRH) due to a nonsense homozygous mutation in the TRH receptor (TRHR) gene (p.R17X). We examined the in ...
Whether hormone supplementation is necessary for infants with transient hypothyroxinemia of prematurity (THOP) remains controversial, and further analysis of the hypothalamus–pituitary–thyroid axis of ...
Levels of thyroid hormones in serum are tightly regulated by the hypothalamic-pituitary-thyroid axis (Figure 1). Hypothalamic TSH-releasing hormone (TRH) is secreted mainly from the paraventricular ...
New research shows that it may be safe for patients taking thyroxine replacement to have low but not suppressed thyroid stimulating hormone (TSH) levels. The research shows for the first time that it ...
Systemic TH levels are maintained by the classical negative feedback loop involving the hypothalamus-pituitary-thyroid (HPT) axis (Figure 1). Thyrotropin releasing hormone (TRH) is synthesized in the ...
Dr. Mestman is Professor in the Departments of Medicine and Obstetrics and Gynecology, University of Southern California, Los Angeles, Calif. Mestman JH. Perinatal Thyroid Dysfunction: Prenatal ...
TSH in pars distalis (PD-TSH) is controlled by the hypothalamus -- pituitary gland -- thyroid gland (HPT) axis. The hypothalamus secretes the thyrotropsin-releasing hormone (TRH), which stimulates the ...
The thyroid, a butterfly-shaped gland at the base of the neck, regulates metabolism, energy levels, digestion, and reproductive health. Thyroid disorders are among the most common endocrine conditions ...
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