Make no mistake, addiction is a neurological brain disorder. When the subject of addiction comes up, people often lean on familiar explanations. “They just need more willpower.” “Why can’t they stop ...

For years, addiction was seen as a matter of personal failure—a bad habit or a lack of discipline. People believed those who struggled with substance abuse could stop if they simply wanted to. But ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Rutgers‑led study of 2.2 million people finds addiction risk is driven more by genes tied to impulse control and reward ...

Researchers analyze 2.2 million genomes to show that addiction risk is primarily driven by broad genes affecting brain wiring ...

Explore the connections between the world of neuroscience and nuances of substance use disorders with our inaugural episode of In Such a Place. We’ll speak with Dr. Anna Radke, a leading expert in the ...

A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.

The brain is a master controller, organized into large-scale neural networks that directly affect whether people with addictions break free or surrender. Research has identified a key site, the action ...

Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

What is addiction, and how can we stop it? The complexities of addiction have stumped scientists for decades. Today, with 48 million Americans over the age of 12 suffering from a substance use ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...