The right-wing pundit's clash with the senator comes as Republicans debate whether or not to dig deeper into conflict in the Middle East.

Iran's supreme leader on Wednesday rejected U.S. calls for surrender in the face of more Israeli strikes and warned that any military involvement by the Americans would cause "irreparable damage to them.

Israel has said it does not target Iranian civilians, but hundreds have died in the violence, among them a poet and her family, an equestrian and a graphic designer.

Iran’s embattled leaders have found themselves in an existential struggle domestically to protect nearly a half-century of rule.