FierceBiotech15h
In 2 papers, researchers describe potential new neurodegenerative disease treatment approach
The team engineered genes to code for the RING constructs and delivered them to mice using an adenovirus vector, commonly ...
Hantavirus Alert: Two Mice from Trails at San Onofre State Beach Test Positive
San Diego County public health employees collected two mice from trails around San Onofre State Beach that tested positive ...
Hantavirus detected in mice at San Onofre State Beach
The potentially deadly hantavirus has been detected in two mice at San Onofre State Beach, San Diego County officials said ...
The EMBO Journal10d
Gene therapy for epilepsy targeting neuropeptide Y and its Y2 receptor to dentate gyrus granule cells
Co-expressing NPY and its inhibitory receptor Y2 in excitatory hippocampal cells allows inhibitory autoregulation of ...
New therapy that targets and destroys tau tangles: A promising Alzheimer's disease treatment
Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
eLife4d
Pathogenic LRRK2 causes age-dependent and region-specific deficits in ciliation, innervation and viability of cholinergic neurons
Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...