Background: The implementation and clinical impact of machine learning–based early warning systems for patient deterioration in hospitals have not been well described. We sought to describe the ...

Background: Ground-level falls are common among older adults and are the most frequent cause of traumatic intracranial bleeding. The aim of this study was to derive a clinical decision rule that ...

The incidence of chlamydia and gonorrhea, 2 common sexually transmitted infections, is increasing. Annual asymptomatic screening for chlamydia and gonorrhea should be performed in all sexually active ...

Recommendation The Canadian Task Force on Preventive Health Care recommends against instrument-based depression screening using a questionnaire with cut-off score to distinguish “screen positive” and ...

Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...

KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department.[1][1] It is a clinical spectrum of ...

Scope The Canadian Stroke Best Practice Recommendations are intended to provide up-to-date, evidence-based guidelines for the prevention and management of conditions that are of concern to the Heart ...

KEY POINTS Indigenous Peoples in Canada benefit from regaining access to and strengthening traditional cultural ways of life, including health and healing practices. Many Indigenous communities are ...

Cannabinoid levels can be increased by other medications Delta-9-tetrahydrocannabinol (THC) and cannabidiol are pharmacologically active cannabinoids in marijuana that are metabolized by cytochrome ...

BACKGROUND: The Global Burden of Disease Study represents a large and systematic effort to describe the burden of diseases and injuries over the past 3 decades. We aimed to summarize the Canadian data ...

Chronic noncancer pain includes any painful condition that persists for at least three months and is not associated with malignant disease.[1][1] According to seven national surveys conducted between ...

Croup develops in more than 80 000 Canadian children each year, making it the second most common cause of respiratory distress in the first decade of life. 1, 2 It affects boys more than girls (1.4:1) ...