The growth rate of the atmospheric abundance of methane (CH 4) reached a record high of 15.4 ppb yr −1 between 2020 and 2022, but the mechanisms driving the accelerated CH 4 growth have so far been ...

Cell-based therapy using satellite stem cells (SSCs) holds tremendous potential for enhancing muscle regeneration. However, conventional isolation methods often yield heterogeneous cell populations ...

As former EPA and ORD scientists, we argue that dismantling ORD would not only jeopardize human and environmental health, but also weaken American science and global competitiveness. ORD’s vital—yet ...

Crystallization of the lunar magma ocean yielded a chemically unique liquid residuum named KREEP. This component is expressed as a large patch on the near side of the Moon and a possible smaller patch ...

Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Heritable microbes can regulate insect reproduction in diverse ways (1). For example, some symbionts which have been called reproductive manipulators, cause cytoplasmic incompatibility, male-killing, ...

Using novel mouse models, we establish cyclin-dependent kinase 12 (CDK12) as a bona fide tumor suppressor gene in tubo-ovarian high-grade serous carcinoma, demonstrating that its loss drives increased ...

Nav1.8 voltage-gated sodium channels are strongly expressed in human primary pain-sensing neurons (nociceptors) and a selective Nav1.8 inhibitor VX-548 (suzetrigine) has shown efficacy for treating ...

In This IssueThe chemical by-products of dimethyl sulfide (DMS), a source of atmospheric sulfur emissions from the ocean, contribute to aerosol formation, influencing cloud formation, albedo, and ...

Long-term light at night (LAN) exposure poses a health threat to nocturnal lab animals. Whether diurnal animals suffer the same deleterious effect imposed by LAN and how it works are still open ...

In the field of cooperation, the vast majority of research revolves around proposing and analyzing mechanisms for cooperation. These mechanisms respond to plausible hypothesis and tend to shift ...

Circulating monocytes are recruited to the tumor microenvironment, where they can differentiate into macrophages that mediate tumor progression. To reach the tumor microenvironment, monocytes must ...