SUMMARY: Period cramps happen because the uterus releases prostaglandins (chemicals that tell the uterus to contract, to help shed the uterine lining). Higher prostaglandin levels cause more intense and more frequent contractions, which can temporarily decrease blood flow and oxygen delivery to the uterine muscle. Less oxygen = interpreted as pain. The uterus is also connected to the nervous system, so those contractions can reflexively tighten nearby abdominal muscles, adding to the general cra
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